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Pembrolizumab-Induced Rhabdomyolysis in a Clear Cell Renal Cell Carcinoma Patient: A Case Report

Mohammad Altermanini, Khaled Ali, Wisam Alwassiti, Suliman Almohtasib, Nabil E. Omar, Abdulaziz Zafar

CASE REPORTS IN ONCOLOGY（2023）

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Abstract
Pembrolizumab is one of the approved treatments for many types of cancer including clear cell renal cell carcinoma (ccRCC). It has improved the prognosis of renal cell carcinoma, yet has many possible immune-related side effects. We discuss a rare case of rhabdomyolysis in an ccRCC patient treated with pembrolizumab. The case was complicated with acute kidney injury and severe hypothyroidism, which can be attributed to pembrolizumab.
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Key words
Pembrolizumab,Rhabdomyolysis,Renal cell carcinoma,Oncology
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