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基于"窍"理论辨治阿尔茨海默病

MA Rui, LAN Wenyu,WANG Xiaorui, SUN Qi, ZHU Jingxin,CHAI Zekun, WANG Le

Acta Chinese Medicine and Pharmacology(2023)

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Abstract
阿尔茨海默病(AD)是临床上最常见的中枢神经系统退行性疾病之一,其发病率逐年增加,具有高致残率和高死亡率的特点,中医药诊治AD取得较好效果.国医大师卢芳基于"窍"理论,认为本病的病位在心窍和脑窍,核心病机多为"痰瘀阻窍、神机失用",治疗以"化痰逐瘀、醒神开窍"为主.卢芳教授在治疗AD时,运用鼻溶栓剂联合脑灵通窍汤作为AD的基础方.本文系统归纳总结了基于"窍"理论辨治AD的思路,并附验案1 则以佐证.
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Key words
'Orifice'theory,Alzheimer's Disease,Nasal thrombolytic suppository,Naoling Tongqiao decoction
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