Adult Cerebral Malaria: Acute and Subacute Imaging Findings, Long-term Clinical Consequences

Charles Coughlan,Hans Rolf Jaeger, David Brealey,Francesco Carletti,Harpreet Hyare,Rajyabardhan Pattnaik,Praveen K. Sahu,Sanjib Mohanty,Sarah Logan,Angelika Hoffmann,Samuel C. Wassmer, Anna M. Checkley

CLINICAL INFECTIOUS DISEASES（2024）

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摘要

Cerebral malaria is an important cause of mortality and neurodisability in endemic regions. We show magnetic resonance imaging (MRI) features suggestive of cytotoxic and vasogenic cerebral edema followed by microhemorrhages in 2 adult UK cases, comparing them with an Indian cohort. Long-term follow-up images correlate ongoing changes with residual functional impairment.

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malaria,cerebral malaria,neuro-imaging,MRI,neuro-disability

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