Hydralazine combined with conventional therapy improved outcomes in severe systolic dysfunction and mitral regurgitation.

Shih-Hung Hsiao,Chao-Sheng Hsiao,Jau-Wen Shiau,Kuan-Rau Chiou

ESC heart failure（2023）

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Abstract

When administered without inadequate preload, combining early up-titration of hydralazine with EBMs improves outcome in patients with severe systolic dysfunction and significant MR, and it is safe and well tolerated.

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