Formation, biomolecular interaction and cytotoxicity studies of new organoruthenium Schiff base compounds

New organoruthenium(II) Schiff base compounds were synthesized and characterized. These metal compounds illustrated optimal affinities towards Bovine Serum Albumin and Deoxyribonucleic acid as well as could inhibit Topoisomerase I function. Anticancer studies revealed that, in general, the compounds display selectivity for breast cancer cells compared to cervical cancer cells.