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Development of new cobalt, copper, and zinc complexes of Schiff-base ligands as prospective chemotherapeutic agents

Vigneswari Sankara Narayanan,Archana Rajendran,Srikrishna Mudradi,Soven Dhawa,Sreeja Rajendran,Kondapa Naidu Bobba,Jeya Rajendran,Prasanna Ramani

Polyhedron（2023）

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Abstract
•Co, Cu, & Zn complexes of bidentate ligands were synthesized and characterized.•The complexes were observed to have high spin and distorted octahedral geometry.•Cu-complexes showed good antioxidant and anticancer potential.
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Key words
Chemotherapeutic agents,Bidentate Schiff-base,Thiosemicarbazone,Transition metal complexes,CT-DNA binding,Antioxidant,Cytotoxicity
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