Quercetin suppresses cell proliferation using the apoptosis pathways in MCF-7 and MDA-MB-231 human breast carcinoma cells in monolayer and spheroid model cultures
South African Journal of Botany(2023)
Abstract
•The most common cancer type worldwide is breast cancer.•Significant changes were detected in the expression of the Endo-G, Cas-3, Cas-8 and Cas-9 genes on breast carcinoma cell lines.•Guercetin suppresses cell proliferation and induces apoptosis both in monolayer and spheroid cultures.
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Key words
quercetin suppresses cell proliferation,human breast carcinoma cells,apoptosis pathways,breast carcinoma
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