Paradoxical inflammatory blepharitis in a patient with Crohn's disease.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus(2023)
摘要
We report the case of a 15-year-old boy with severe inflammatory blepharitis who was being treated with a TNFα inhibitor for Crohn's disease (CD). This case shows the potential utility of a skin biopsy in distinguishing metastatic CD associated with granulomatous blepharitis from a paradoxical blepharitis induced by anti-TNFα. It also demonstrates that ustekinumab can be considered in patients with CD who cannot tolerate TNFα inhibitors because of cutaneous paradoxical reactions.
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