Autobahn der Zelle: Wie das SARS-CoV-2-Spike-Protein durch die Zelle reist

Viruses employ cellular host factors not only for replication and transcription but also for transport and assembly. Rab-GTPases, as master regulators of intracellular trafficking pathways, are commonly involved host factors and useful tools for identification of transport pathways used but certain viruses. Here, we present Rab1B as an essential host factor for trafficking and maturation of the SARS-CoV-2 spike protein.