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抗疟药研究进展

WEI Luanting, LI Runze, GUAN Liangchao, ZHANG Qianyu, LI Cheng,CAO Yaming,ZHAO Yan

Chinese Journal of Parasitology and Parasitic Diseases（2023）

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Abstract
疟原虫的耐药性问题是药物治疗疟疾面临的最大挑战.疟原虫对包括青蒿素在内的常见传统抗疟药均产生了不同程度的耐药性,因此,传统药物的改进,以及对新型药物的研发刻不容缓.本文在系统地梳理传统抗疟药的耐药机制、传统药物的改进方法及优化成果和新型抗疟药研究进展的基础上,对疟疾防治策略进行讨论.
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Key words
Anti-malarial drugs,Drug resistance analysis,New drug development,Targeted drug,prevention strategy
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