Preparation of double-system imprinted polymer-coated multi-walled carbon nanotubes and their application in simultaneous determination of thyroid-disrupting chemicals in dust samples

Dust ingestion is a significant route of human exposure to thyroid-disrupting chemicals (TDCs), and simultaneous determination of multi-contaminants is a great challenge for environmental monitoring. In this study, molecularly imprinted polymer-coated multi-walled carbon nanotubes using thyroxine as the template were synthesized for highly selective TDCs capture. This polymer was prepared by integrating the atom transfer radical polymerization using 2-(3-indol-yl)ethylmethacrylamide as the monomer with the self-polymerization of dopamine. Construction of double-system imprinted cavities could significantly improve their selective recognition performance for TDCs and the coincidence rate reached 88.5 %. The prepared polymers were applied as the solid phase extraction adsorbent to simultaneously determine 7 groups of 35 TDCs. The proposed method showed wide linear range (0.25-1000 ng L-1), low limits of detection (0.02-0.23 ng L-1) and acceptable recoveries (81.8 %-103.5 %). The occurrence and distribution of TDCs were then studied in indoor dust samples (n = 65) collected from four cities in China. We found that tetrabromobisphenol A was the predominant compound and perfluorinated compounds were the most abundant TDCs. In addition, the distribution ratio of TDCs varied between regions. This study provides an efficient technology for direct exposure assessment of multi-contaminants.