Disturbed sleep is associated with reduced verbal episodic memory and entorhinal cortex volume in younger middle-aged women with risk-reducing early ovarian removal.

Nicole J Gervais,Laura Gravelsins,Alana Brown,Rebekah Reuben,Mateja Perovic,Laurice Karkaby,Gina Nicoll, Kazakao Laird,Shreeyaa Ramana,Marcus Q Bernardini,Michelle Jacobson,Lea Velsher,William Foulkes,M Natasha Rajah,Rosanna K Olsen,Cheryl Grady,Gillian Einstein

Frontiers in endocrinology（2023）

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摘要

Together, these findings confirm an association between ovarian hormone loss and insomnia symptoms, and importantly, identify an younger onset age in women with early ovarian removal, which may contribute to poorer cognitive and brain outcomes in these women.

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disturbed sleep,verbal episodic memory,early ovarian removal,entorhinal cortex,entorhinal cortex volume,middle-aged,risk-reducing

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