Treatment of Mpox with Suspected Tecovirimat Resistance in Immunocompromised Patient, United States, 2022

Caitlin A. Contag, Leah Mische, Isabel Fong,Abraar Karan, Akanksha Vaidya,David W. Mccormick, William Bower,Jill K. Hacker, Kelly Johnson, Perla Sanjuan, Linda Crebbin, Caroline Temmins,Harleen Sahni, Yael Bogler, Joseph D. Cooper, Supriya Narasimhan

EMERGING INFECTIOUS DISEASES（2023）

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摘要

Reports of tecovirimat-resistant mpox have emerged after widespread use of antiviral therapy during the 2022 mpox outbreak. Optimal management of patients with persistent infection with or without suspected resistance is yet to be established. We report a successfully treated case of severe mpox in California, USA, that had suspected tecovirimat resistance.

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