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Ultrasound assisted synthesis of 4-(1H-indol-3-yl)thieno[2,3-d]pyrimidine derivatives via AcOH mediated CC bond forming reaction

Sowmy Adapa,Unati Sai Kodali,Amit Kumar Taneja, Vinu Bandaru,Bhuvan Tej Mandava, Bhagavatula Balakrishna,Bhagya Tej Mandava,Naresh Panigrahi, Mandava Venkata Basaveswara Rao,Manojit Pal

Tetrahedron Letters（2023）

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Abstract
A simple, convenient and straightforward approach is described for the sonochemical synthesis of 4-(1H-indol-3-yl)thieno[2,3-d]pyrimidines as potential inhibitors of TNF-α.
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Key words
Thieno[23-d]pyrimidine,Ultrasound,AcOH,TNF-α
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