Standardized seed extract of Cajanus cajan (L) Millsp. produced antinociceptive and anti-inflammatory actions through inhibition of inflammatory mediators and activation of opioidergic signaling

Phytomedicine Plus(2023)

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摘要
•C. cajan seeds extract possesses antinociceptive and anti-inflammatory actions.•C cajan-induced antinociception through opioidergic and nitrergic pathways.•Anti-inflammatory activity through inhibition of cyclooxygenase-2 enzyme.•The antinociceptive effect of CC due the presence of pinostrobin, luteolin and cajanin.•Pinostrobin, Physcion& lupeol showed potent interaction with MOR, COX-2 and PLA2.
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关键词
cajanus cajanus,anti-inflammatory mediators,standardized seed extract
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