Research funding for newborn health and stillbirths 2011-20: a systematic analysis of levels and trends

Priyesh Agravat, Eva M. Loucaides,Meghan Bruce Kumar, Anna Howells, Alexandra Molina Garcia,Ismail Sebina, Nuria Balanza,Elizabeth J. A. Fitchett,Joy E. Lawn

LANCET GLOBAL HEALTH(2023)

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摘要
Background Worldwide, an estimated 44 million newborn deaths and stillbirths occurred in 2020, and 98% of these deaths occurred in low-income and middle-income countries (LMICs). We aimed to analyse new research grants for newborns and stillbirth awarded by major funders in 2019-20, and all research funding allocated to LMIC-based institutions in 2011-20.Methods For this systematic analysis, we searched Dimensions, the world's largest research funding database, for grants relevant to neonatal and stillbirth research. Included grants were categorised by in-depth content analysis, with descriptive quantitative analyses by funder and recipient countries, research pipeline, topic, and year.Findings Globally, in 2019-20, major funders awarded a mean annual total of US$5771 million per year for newborn and stillbirth research (mean total of 550 grants per year). $1663 million (288%) of $5771 million was directed to small and vulnerable newborn research, but only $84 million (15%) was directed to stillbirth research. The majority of funding, $5370 million (930%), was allocated to organisations based in high-income countries. Between 2011 and 2020, LMIC-based recipients were named on 1985 grants from all funders worth $4867 million, of which $731 million (150%) was allocated to small and vulnerable newborn research and $120 million (25%) was allocated to stillbirth research. Most LMIC funding supported preclinical or observational studies ($2368 million [487%] of $4867 million), with implementation research receiving only $139 million (29%).Interpretation Although investment in research related to neonatal health and stillbirths has increased between 2011 and 2020, there are marked disparities in distribution geographically, between major causes of mortality, and among research pipeline types. Stillbirth research received minimal funding in both high-income countries and LMICs, despite a similar number of deaths compared with neonates. Direct investment in LMIC-led research, especially for implementation research, could accelerate the slow global progress on stillbirth prevention and newborn survival.
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newborn health,stillbirths,research funding
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