子宫内膜样癌伴有微乳头结构和微囊、伸长及碎片状浸润1例

FU Jiaju, ZHOU Xiaoli,GU Wenxian, GAO Wei,CHENG Yuqing

Journal of Clinical and Pathological Research(2023)

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Abstract
子宫内膜样癌伴有微乳头结构和微囊、伸长及碎片状(microcystic,elongated and fragmented,MELF)浸润者罕见.常州市第二人民医院收治1例52岁的女性子宫内膜样癌患者,其病理标本中出现了微乳头结构,微乳头形态类似乳腺浸润性微乳头状癌,由簇状或小巢团状肿瘤细胞组成,缺乏纤维血管轴心,与周围组织存在空隙,异型性明显;在免疫组织化学染色中显示特征性的黏蛋白1外缘染色和E-钙黏蛋白杯状染色.肿瘤浸润前沿同时可见MELF 浸润方式.肿瘤浸润深肌层,可见脉管癌栓和1枚淋巴结隐匿性癌转移.患者术后接受化学治疗和放射治疗,恢复良好,随访53个月无复发或转移.临床上此类病例具有高侵袭性的生物学行为,容易漏诊,需要予以重视.
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Key words
endometrioid carcinoma,micropapillary,microcystic,elongated and fragmented pattern invasion
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