Cytokine Profiling of Cyst Fluid and Tumor-Associated Macrophages in Cystic Vestibular Schwannoma.

Eric Nisenbaum,Matthew Wiefels,Julia Telischi,Mikhail Marasigan,Vivek Kanumuri,Stefanie Pena,Torin Thielhelm,Olena Bracho,Rita Bhatia,Tricia Scaglione,Fred Telischi,Cristina Fernandez-Valle,Xue-Zhong Liu,Evan Luther,Jacques Morcos,Michael Ivan,Christine T Dinh

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology（2023）

引用 0|浏览7

暂无评分

摘要

Cyst fluid from cystic VS harbored high levels of osteopontin and MCP-1, which are cytokines important in monocyte recruitment and macrophage polarization. MCP-1 may have a significant role in molding the tumor microenvironment, by polarizing monocytes to CD80+ M1 macrophages in cystic VS. Further investigations into the role of cytokines and macrophages in VS may lead to new avenues for therapeutic intervention.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要