[Association between chronic diseases and possible sarcopenia in middle-aged and older Chinese men: A prospective cohort study].

The risk of possible sarcopenia in the middle-aged and older men with prostatic disease, cognitive impairment or depression was increased by 16% (HR = 1.16, 95% CI: 1.01－1.33), 23% (HR = 1.23, 95% CI: 1.10－1.38) and 12% (HR = 1.12, 95% CI: 1.01－1.24), respectively. The risk in those with one, two or three or more chronic diseases was raised by 22% (HR = 1.22, 95% CI: 1.04－1.42), 20% (HR = 1.20, 95% CI: 1.02－1.42) and 46% (HR = 1.46, 95% CI: 1.25－1.71), respectively, compared with those without chronic diseases, and it was increased in a dose-dependent manner (P < 0.01) Conclusion: Prostatic disease, cognitive impairment and depression increase the risk of possible sarcopenia in middle-aged and older Chinese males, and the risk rises with the increased number of chronic comorbidities.