High-grade medullary thyroid carcinoma with papillary-like nuclear features: A report of five cases.

Naoki Yamao,Mitsuyoshi Hirokawa,Ayana Suzuki,Miyoko Higuchi, Tomo Ishisaka,Akira Miyauchi,Takashi Akamizu

Diagnostic cytopathology（2023）

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摘要

Our work suggests that papillary-like nuclear features in MTC may be associated with high-grade tumors. These findings may be cytologically indicative of high-grade tumors other than necrosis or mitosis.

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关键词

calcitonin doubling time, high-grade medullary carcinoma, Ki-67 labeling index, lobulated nuclei, nuclear groove, papillary-like nuclear features, thyroid

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