Insulin resistance and central obesity determine hepatic steatosis and explain cardiovascular risk in steatotic liver disease.

Georg Semmler,Lorenz Balcar,Sarah Wernly,Andreas Völkerer,Lorenz Semmler,Laurenz Hauptmann,Bernhard Wernly,Elmar Aigner,David Niederseer,Christian Datz

Frontiers in endocrinology（2023）

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摘要

Although hepatic steatosis is associated with increased central obesity and insulin resistance, metabolic dysfunction rather than hepatic steatosis explains cardiovascular risk in these patients.

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关键词

MASLD, NAFLD, steatotic liver disease, metabolic syndrome, insulin resistance, SCORE2

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