How sleep quality affects activities of daily living in Parkinson's disease: the mediating role of disease severity and the moderating role of cognition.

Yajun Luo,Junyi Liu,Dongqin Chen,Manhua Liu, Yuan Yuan,Jingzhe Hu, Jiayu Wu,Fen Wang,Chunfeng Liu,Juping Chen,Chengjie Mao

Frontiers in aging neuroscience（2023）

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摘要

Disease severity mediated the association between sleep quality and ADL, good cognition significantly reduced disease severity's mediating influence on the relationship between sleep quality and ADL. Our study indicated a close relationship between ADL and sleep and cognition in PD, and also provided new insights into the overall management of PD and a better quality of life of PD patients.

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关键词

Parkinson's disease, activities of daily living, disease severity, sleep quality, cognition

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