Functional metagenomic and metabolomics analysis of gut dysbiosis induced by hyperoxia.
Frontiers in microbiology（2023）
Abstract
Hyperoxia leads to gut dysbiosis by eliminating beneficial and oxygen strictly intolerant with genomic dysfunction of carbohydrate and lipid metabolism. In addition, hyperoxia suppresses unsaturated fatty acid metabolism in the gut and inhibits the HIF-1 and glucagon signaling pathways in the serum.
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Key words
gut dysbiosis,metabolomics analysis
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