Gabapentin as a potential biomarker-guided pharmacotherapy in asd

David Cochran,David N. Kennedy,Steven M. Hodge, Arline Mata,Jean A. Frazier

Journal of the American Academy of Child & Adolescent Psychiatry（2023）

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摘要

The objectives are to determine whether social cognition in ASD is associated with Glx (combination of glutamate and glutamine) and gamma-aminobutyric acid (GABA) levels in the anterior cingulate cortex (ACC) and right anterior insula (RAI), and whether gabapentin changes these levels acutely or chronically.

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关键词

gabapentin,pharmacotherapy,biomarker-guided

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