Rare inherited dna variants in ocd identify candidate risk genes and biological pathways

Kiran Masroor,Carolina Cappi, Monicke O. Lima,Thomas V. Fernandez

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY（2023）

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摘要

Whole-exome DNA sequencing (WES) of multiplex families has yet to be leveraged for identifying risk genes in OCD. Here we apply this approach to affected individuals from multiplex families to identify genes and biological processes underlying OCD risk.

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