A new road to STING activation
Nature Chemical Biology（2024）
摘要
ivation of STING-dependent signal transduction results in adaptive immune responses that promote antitumor immunity. A recent study has identified a small-molecule STING agonist that functions by binding to a newly discovered ligandable site to induce high-order STING oligomerization.
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关键词
Cancer therapy,Immunology,Small molecules,Structural biology,Chemistry/Food Science,general,Biochemical Engineering,Biochemistry,Cell Biology,Bioorganic Chemistry
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