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Exploring the Complex Relationship Between Antiepileptic Drugs and Suicidality: A Systematic Literature Review.

Innovations in clinical neuroscience(2023)

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Abstract
Although there were several methodological limitations, this review found an association between levetiracetam use and mental health comorbidities and the occurrence of suicidality in epilepsy. Larger prospective, randomized studies that overcome the limitations of current studies are required to provide definitive evidence on the occurrence of suicidality in patients with epilepsy and AED use.
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Key words
antiepileptic drugs,suicidality,systematic literature review
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