Native mass spectrometry interrogation of complexes formed during targeted protein degradation.

Ikhlas M M Ahmed,Rebecca Beveridge

Rapid communications in mass spectrometry : RCM(2023)

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摘要
Here, we provide step-by-step instructions for the sample preparation of PROTAC complexes and their nMS interrogation to obtain optimal information on their binding modes.
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关键词
native mass spectrometry interrogation,mass spectrometry,protein,complexes,degradation
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