MRI Biomarkers and Their Future Impact on Nonalcoholic Fatty Liver Disease.

HomeRadiologyVol. 309, No. 1 PreviousNext Reviews and CommentaryEditorialMRI Biomarkers and Their Future Impact on Nonalcoholic Fatty Liver DiseaseKazuto Kozaka , Osamu MatsuiKazuto Kozaka , Osamu MatsuiAuthor AffiliationsFrom the Department of Radiology, Kanazawa University Graduate School of Medical Sciences, 13-1, Takaramachi, Kanazawa, Ishikawa 920-8641, Japan.Address correspondence to K.K. (email: [email protected]).Kazuto Kozaka Osamu MatsuiPublished Online:Oct 10 2023https://doi.org/10.1148/radiol.232420MoreSectionsFull textPDF ToolsAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In References1. Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology 2016;64(1):73–84. Crossref, Medline, Google Scholar2. Profiles. Quantitative Imaging Biomarkers Alliance Wiki. https://qibawiki.rsna.org/index.php/Profiles. Accessed September 17, 2023. Google Scholar3. Fowler KJ, Venkatesh SK, Obuchowski N, et al. Repeatability of MRI biomarkers in nonalcoholic fatty liver disease: the NIMBLE Consortium. Radiology 2023;309(1):e231092. Google Scholar4. Sanyal AJ, Shankar SS, Calle RA, et al. Non-Invasive Biomarkers of Nonalcoholic Steatohepatitis: the FNIH NIMBLE project. Nat Med 2022;28(3):430–432. Crossref, Medline, Google Scholar5. Murphy J, Bacon SL, Morais JA, Tsoukas MA, Santosa S. Intra-Abdominal Adipose Tissue Quantification by Alternative Versus Reference Methods: A Systematic Review and Meta-Analysis. Obesity (Silver Spring) 2019;27(7):1115–1122. Crossref, Medline, Google Scholar6. Hu HH, Yokoo T, Bashir MR, et al; RSNA Quantitative Imaging Biomarkers Alliance PDFF Biomarker Committee. Linearity and Bias of Proton Density Fat Fraction as a Quantitative Imaging Biomarker: A Multicenter, Multiplatform, Multivendor Phantom Study. Radiology 2021;298(3):640–651. Link, Google Scholar7. Zhang YN, Fowler KJ, Ozturk A, et al. Liver fibrosis imaging: A clinical review of ultrasound and magnetic resonance elastography. J Magn Reson Imaging 2020;51(1):25–42. Crossref, Medline, Google Scholar8. Serai SD, Obuchowski NA, Venkatesh SK, et al. Repeatability of MR Elastography of Liver: A Meta-Analysis. Radiology 2017;285(1):92–100. Link, Google Scholar9. Caussy C, Reeder SB, Sirlin CB, Loomba R. Noninvasive, Quantitative Assessment of Liver Fat by MRI-PDFF as an Endpoint in NASH Trials. Hepatology 2018;68(2):763–772. Crossref, Medline, Google Scholar10. Imajo K, Kessoku T, Honda Y, et al. MRI-Based Quantitative R2* Mapping at 3 Tesla Reflects Hepatic Iron Overload and Pathogenesis in Nonalcoholic Fatty Liver Disease Patients. J Magn Reson Imaging 2022;55(1):111–125. Crossref, Medline, Google ScholarArticle HistoryReceived: Sept 9 2023Revision requested: Sept 15 2023Revision received: Sept 16 2023Accepted: Sept 19 2023Published online: Oct 10 2023 FiguresReferencesRelatedDetailsAccompanying This ArticleRepeatability of MRI Biomarkers in Nonalcoholic Fatty Liver Disease: The NIMBLE ConsortiumOct 10 2023RadiologyRecommended Articles Repeatability of MRI Biomarkers in Nonalcoholic Fatty Liver Disease: The NIMBLE ConsortiumRadiology2023Volume: 309Issue: 1Distinguishing between Hepatic Inflammation and Fibrosis with MR ElastographyRadiology2017Volume: 284Issue: 3pp. 694-705Emergence of 3D MR Elastography–based Quantitative Markers for Diffuse Liver DiseaseRadiology2021Volume: 301Issue: 1pp. 163-165Quantification of Liver Fat Content with CT and MRI: State of the ArtRadiology2021Volume: 301Issue: 2pp. 250-262US-derived Fat Fraction Screening of Hepatic SteatosisRadiology2022Volume: 304Issue: 1pp. 83-84See More RSNA Education Exhibits Imaging Techniques for Quantification of Liver Fat and IronDigital Posters2022The Many Faces Of The Fat Liver: A Guide To Recognize All Patterns Of Non-alcoholic Fatty Liver Disease (NAFLD) On Multiparametric Hepatic MRIDigital Posters2021Diffuse Liver Disease and Its Quantification in MRI for RookiesDigital Posters2022 RSNA Case Collection Hepatic SteatosisRSNA Case Collection2021Primary HemochromatosisRSNA Case Collection2021Multifocal hepatic steatosis RSNA Case Collection2020 Vol. 309, No. 1 Metrics Altmetric Score PDF download