Adrenal Metastases Are Associated with Poor Outcomes in Patients with Metastatic Clear Cell Renal Cell Carcinoma Treated with Nivolumab in the GETUG-AFU-26 NIVOREN Phase 2 Trial.

Emilien Billon,Cécile Dalban, Stephane Oudard,Christine Chevreau,Brigitte Laguerre, Philippe Barthélémy,Delphine Borchiellini,Lionnel Geoffrois,Sylvie Negrier, Florence Joly,Antoine Thiery-Vuillemin,Marine Gross-Goupil,Frederic Rolland,Frank Priou,Hakim Mahammedi,Florence Tantot,Bernard Escudier,Sylvie Chabaud,Laurence Albiges, Gwenaelle Gravis

European urology oncology（2023）

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摘要

Our study showed that metastasis in the adrenal glands could be an independent factor associated with poor response to immunotherapy and survival for patients with metastatic kidney cancer. It would be useful to evaluate the prognostic value of adrenal gland metastasis in patients treated with immunotherapy combinations or immunotherapy agents combined with drugs called tyrosine kinase inhibitors.

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