Protective effect of Huangqi-Guizhi-Wuwutang against cyclophosphamide-induced spermatogenesis dysfunction in mice by promoting steroid hormone biosynthesis.

Yuan Zhao,Jinru Wu,Xiangbin Li,Qiugu Chen,Zhiming Hong,Lin Zheng,Shiying Huang,Pingli Mo,Changhui Li,Rui Wang,Qiuyan Guo,Shangbin Zhang,Jianping Chen

Journal of ethnopharmacology（2023）

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摘要

Our data has demonstrated the effectiveness of HGW in improving CTX-induced spermatogenic dysfunction by enhancing hormonal steroid synthesis in a model system, indicating the potential chemoprotective effects of HGW against CTX-induced spermatotoxicity.

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关键词

Huangqi-Guizhi-Wuwutang,Spermatogenesis dysfunction,Spermatogenic toxicity,Cyclophosphamide,Testosterone,TM3 cell

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