Neurobiological correlation between phosphorylated tau and mood symptoms in memory clinic patients.

Takashi Ozaki,Naoki Hashimoto,Niki Udo,Hisashi Narita,Shin Nakagawa,Ichiro Kusumi

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society（2023）

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摘要

We provide new evidence for a negative correlation between p-tau and depression and apathy of NPS, which may be influenced by APOE ε4. Future longitudinal studies are required to confirm the utility of p-tau for predicting the course of mood symptoms in patients with cognitive decline.

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关键词

Alzheimer's disease, apolipoprotein E gene, mild cognitive impairment, neuropsychiatric symptoms, phosphorylated tau

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