Visible-light-induced photocatalyst-free dearomative amidation of phenol derivatives

TETRAHEDRON LETTERS(2023)

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摘要
Herein, a simple protocol has been outlined for visible-light-induced dearomative amidation reaction of phenol derivatives to afford spirolactams with broad substrate scope. The amidation was found to proceed smoothly without any photocatalyst at room temperature, and the desired spirolactams were obtained in 23%-87% yields.
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关键词
Amidyl radical,Dearomative amidation,Photocatalyst-free,Spirolactams,Visible light photocatalysis
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