Robotic and Navigated Pedicle Screws Are Safer and More Accurate than Freehand Screws: A Systematic Review and Meta-Analysis
NEUROSURGERY(2023)
Abstract
INTRODUCTION: Navigation and robotic pedicle screw placement systems have been developed to improve the accuracy of screw placement. However, the literature comparing the safety and accuracy of robotic and navigated screw placement with freehand screw placement in thoracolumbar spine surgery has been limited. METHODS: PubMed and EMBASE were systematically searched according to PRISMA guidelines. The search included indexed terms and text words from database inception to the date of the search (April 7th, 2022). Only randomized controlled trials comparing robotic assisted or navigated screws with fluoroscopic freehand screws in the thoracolumbar spine were included. Data and estimates were pooled using random-effects meta-analysis. Risk of bias was assessed using the Joanna Briggs Institute risk of bias tool. The main outcome measures were odds ratio estimates for screw accuracy according to the Gertzbein-Robbins scale and relative risk for various complications. RESULTS: A total of 14 papers encompassing 12 randomized controlled trials were identified. The pooled analysis demonstrated that robotic and navigated pedicle screw placement techniques were associated with increased odds of screw accuracy (OR 2.66, 95% CI 1.24-5.72, p = 0.0118). Robotic and navigated screw placement was associated with a lower risk of facet joint violations (RR 0.09, 95% CI 0.02-0.38, p = 0.0011) and major complications (RR 0.31, 95% CI 0.11-0.84, p = 0.0215). No differences were found in nerve root injury (RR 0.50, 95% CI 0.11-2.30, p = 0.3704), return to the operating room for screw revision (RR 0.28, 95% CI 0.07-1.13, p = 0.0744). CONCLUSIONS: These analyses suggest that robotic and navigated screw placement techniques are associated with higher odds of screw accuracy and superior safety profile compared to freehand techniques. Additional randomized controlled trials will be needed to further validate these findings.
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Key words
navigated pedicle screws,freehand screws,robotic,systematic review,meta-analysis
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