Five years of antibiotic consumption for urinary tract infection patients in Indonesia's Provincial Public Hospital

Ikhwan Yuda Kusuma,Dian Ayu Eka Pitaloka, Noorma Devita Arbi, Sunarti Sunarti,Hening Pratiwi, Ahmed Altayeb Ali Omer,Muh. Akbar Bahar

PHARMACIA(2023)

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摘要
This retrospective study aimed to analyze antibiotic utilization and trends in urinary tract infection (UTI) patients without comorbidities at a Provincial Public Hospital in Indonesia. The data of 183 eligible patients who received antibiotics for UTI treatment from 2017 to 2021 were analyzed using the anatomical therapeutic chemical (ATC) classification system. Antibiotic utilization was measured in Defined Daily Dose (DDD) per 100 patient-days and Drug Utilization 90% (DU 90%) index. The study revealed fluctuating utilization, with 2018 (51.32 DDD/100 patient-days) and 2017 (37.22 DDD/100 patient-days) showing the highest and lowest antibiotic utilization, respectively. The most frequently prescribed antibiotics were ceftriaxone injection, cefixime oral, and levofloxacin injection, while ampicillin and amoxicillin oral were the least utilized. These findings provide valuable insights into antibiotic prescribing patterns for UTIs, highlighting fluctuating antibiotic utilization and the need for appropriate antibiotic stewardship strategies in primary care settings.
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关键词
drug utilization study, antibiotic, ATC DDD, urinary tract infections, Indonesia
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