Synthesis of Molecularly Imprinted Polymer Based on "Weak" Halogen-,r Interaction for Recognition of Halogenated Benzenes

Development of selective molecular recognition materials is an urgent issue for precise concentration regulations of each isomer with different environmental toxicity. Molecularly imprinted polymers are well-known artificial materials with selective molecular recognition abilities. Then, a direct approach to achieving selective recognition of halogenated aromatic compounds is synthesis of molecularly imprinted polymer by using highly specific intermolecular interactions with halogen groups. Halogen groups possess electron-deficient regions along the a-bonding direction, and it enables the formation of weak and specific intermolecular interactions between the halogen group and the electron-rich ,r-conjugated surface (X -,r interactions). However, the utilization of X -,r interactions in the synthesis of molecularly imprinted polymers is still limited. In this study, we investigated the synthesis of MIPs based on X -,r interactions and developed selective molecular recognition materials for di-halogenated benzenes.