Color overlay of contrast-enhanced endoscopic ultrasound for pancreaticobiliary disease

Contrast-enhanced endoscopic ultrasound (CE-EUS) has been considered an important examination for visualization of blood flow and for its contribution to more accurate diagnosis in various conditions of the pancreaticobiliary region [1] [2] [3] [4] [5]. However, the conventional black and white mode may limit visual discernibility. A new EUS processor (EU-ME3; Olympus Co., Tokyo, Japan) has been equipped with a novel color overlay mode, which could potentially augment the perception of contrast agents, enhancing the utility of CE-EUS. We present three cases in which the color overlay mode of CE-EUS improved visualization during observation and tissue acquisition ([Video 1]).