Retrospective analysis of metabolic effects of laparoscopic gastric plication and single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S)

AIM: The aim of this study is to investigate the clinical outcomes of patients with type 2 diabetes mellitus (T2DM) who underwent laparoscopic gastric plication (LGP) or single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) and analyze the postoperative first-year results of these two operations. METHODS: Forty-three patients who have undergone LGP and 36 patients who had undergone SADI-S were included in this study. Baseline and postoperative first-year data of patients with T2DM who have undergone LGP or SADI-S in our clinic between January 1, 2013, and June 30, 2016, were retrospectively analyzed. RESULTS: It is understood that both operations maintained a remarkable improvement in blood glucose parameters alongside total cholesterol and triglyceride levels. The complete diabetes remission rate was significantly higher in the SADI-S group than in the LGP group (69.4% vs. 42.1%, p=0.018). LGP group achieved better results than SADI-S on weight loss in terms of the percentage excess weight loss (EWL%) (p<0.001) and the percentage total weight loss (TWL%) (p<0.001). CONCLUSION: In our study, both operations facilitated diabetes remission, and complete remission or improvement was obtained in most of the cases. In addition, statistically significant weight loss was observed in both procedures. Therefore, both bariatric techniques can be chosen for obese diabetic patients considering their priorities and needs.