CD4dimCD8bright T cells are inversely associated with neuro-inflammatory markers among people living with HIV.

Yasmeen A Albalawi,Tanner Shull,Amber Virdi,Caroline Subra,Julie Mitchell,Bonnie M Slike,Ningbo Jian,Shelly J Krebs,Carlo Sacdalan,Nisakorn Ratnaratorn,Denise C Hsu,Nittaya Phanuphak,Serena Spudich,Lydie Trautmann,Lena Al-Harthi

AIDS (London, England)（2023）

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Abstract

CD4dimCD8bright T cells are associated with some anti-inflammatory properties, whereas CD4-CD8+ T cells may contribute to inflammation and injury. Assessing the contrast between these two cell populations in neuroHIV may inform targeted therapeutic intervention to reduce neuroinflammation and associated neurocognitive impairment.

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