Stratifying Response to Stereotactic Radiosurgery for Spinal Metastases by Primary Site Genomic Mutations

E. P. Damron, M. Florez,B. De, K. Huntoon, T. Beckham,C. Wang, J. Li, B. Amini, T. M. Briere, M. C. Tom, C. Tatsui, L. D. Rhines, A. J. Ghia

International journal of radiation oncology, biology, physics（2023）

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摘要

While favorable outcomes among all patients receiving SSRS were seen, increasing BED was associated with more durable LC. Primary site ATM, STK11, and CTNNB1 mutations may be associated with poorer LC following SSRS. Further investigation into the prognostic value of individual mutations and combinations thereof is warranted.

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关键词

spinal metastases,stereotactic radiosurgery,primary site genomic mutations

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