PET-Based Radiogenomics Supports KEAP1/NFE2L2 Pathway Targeting for Non-Small Cell Lung Cancer Treated with Curative Radiotherapy.

V Bourbonne,M Morjani,F Lucia,M Hatt,V Jaouen,S Querellou,D Visvikis,O Pradier, U Schick

International journal of radiation oncology, biology, physics（2023）

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摘要

Our three-step approach enables the prediction of the Mut using PET/CT-extracted radiomics features and efficiently classified patient at risk of LR relapse in an external cohort treated with radiotherapy. This first evidence should be further evaluated on larger cohorts, and implemented in LR risk prediction models.

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