Salvage Abdominoperineal Resection for Locally Recurrent or Persistent Anal Squamous Cell Carcinoma after Definitive Chemoradiation

E. P. Damron,J. McDonald,P. Das, E. J. Koay,A. C. Koong, E. B. Ludmir, S. S. Noticewala,G. L. Smith, C. M. Taniguchi,C. Messick,G. Chang,B. D. Minsky, V. K. Morris, E. Holliday

International journal of radiation oncology, biology, physics（2023）

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摘要

APR is a successful salvage modality for anal squamous cell carcinoma with recurrent or persistent disease after chemoradiation results. Patients with pT3/4 disease, lymphovascular space invasion, surgical margins <2 mm may be associated with higher re-recurrence rates and may benefit from more frequent monitoring or treatment escalation.

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definitive chemoradiation,carcinoma

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