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HPV Infection and Immunohistochemical Analysis of P16, P53, and PD-L1 Expression as Prognostic Biomarkers in Squamous Cell Anal Cancer Patients Receiving Definitive Radiotherapy/Chemoradiotherapy

B. Balci Topuz,F. Sert,M. Sezak, M. Soylu,D. Yalman,S. Ozkok

International journal of radiation oncology, biology, physics（2023）

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Abstract
Patients with HPV- status and/or poor prognostic biomarkers should be identified at diagnosis. Thus, better outcomes can be achieved with different treatment options, such as combining immunotherapy and standard CRT.
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Key words
hpv infection,prognostic biomarkers,cancer patients
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