CDC73 Impairment of MAPK1 Ubiquitination and Activation of the Mtor Signaling Pathway
International journal of radiation oncology, biology, physics(2023)
摘要
CDC73 promoted MAPK1 ubiquitination and degradation so that affected MAPK1 level and subsequently led to breast cancer progression, providing a novel therapeutic strategy to combat cancer.
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关键词
Breast cancer,CDC73,MAPK1,ubiquitination mTOR signaling pathway.
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