Molecular evolution of omicron variant in immunocompromised individuals with chronic SARS-CoV-2 infection.

Camille Vellas,Justine Latour,Pauline Trémeaux,Noémie Ranger,Vénicia Ferrer, Agnès Harter,Romain Carcenac,Pauline Boyer,Sofia Demmou, Pauline Claraz, Nassim Kamar,Jacques Izopet

The Journal of infection（2023）

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摘要

•Immunocompromised patients are at high risk of chronic SARS-CoV-2 infection.•Chronic COVID-19 in immunocompromised patients can lead to new variants.•Apparition of new spike mutation is related to viral rebound.•Virological monitoring of patients with chronic SARS-CoV-2 infection is necessary.

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