The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection.

Malwina Kawka,Renata Płocińska,Przemysław Płociński,Jakub Pawełczyk,Marcin Słomka,Justyna Gatkowska,Katarzyna Dzitko,Bożena Dziadek,Jarosław Dziadek

Frontiers in immunology（2023）

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摘要

Elevated serum hSAA-1 levels in tuberculosis enhance the response of host phagocytes to infection, including macrophages that have not yet been in contact with mycobacteria. SAA induces antigen processing and presentation processes by professional phagocytes reversing the inhibition caused by infection.

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关键词

macrophages,amyloid,mycobacterium tuberculosis,monocyte-derived

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