The promise of targeted protein degradation approaches.

It is an exciting time to be in the targeted protein degradation (TPD) research field. TPD is a promising strategy in therapy development. Newer TPD technologies are being developed for the treatment of cancer and various diseases. Jerry Madukwe, the editor-in-chief of Trends in Pharmacological Sciences (TIPS), asked experts in the field from academia and industry to reflect on the global challenges in the field and what they see as its future.