A Case of Acute Liver Failure Caused by Budd-Chiari Syndrome Salvaged by Brain-Dead Donor Liver Transplantation.
Clinical journal of gastroenterology(2023)
Abstract
A 24-year-old man was admitted to our hospital with abdominal distension. He was found to have acute liver failure and diagnosed with Budd–Chiari syndrome based on angiography and liver biopsy. Liver transplantation was deemed necessary when angiography showed extensive thrombotic occlusion of the hepatic veins and liver biopsy revealed submassive hepatic necrosis. The patient was found to have the JAK2V617F mutation, indicating a myeloproliferative neoplasm as the background disease. He developed hepatic encephalopathy but remained conscious on on-line hemodiafiltration. Brain-dead donor liver transplantation was performed on hospital day 30. Since then, the patient has remained well.
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Key words
Budd–Chiari syndrome,Acute liver failure,Liver transplantation,On-line hemodiafiltration,Myeloproliferative neoplasm
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