Abnormal functional connectivity in radiologically isolated syndrome: A resting-state fMRI study.

Julián Benito-León, Ana Belén Del Pino,Yolanda Aladro,Constanza Cuevas,Ángela Domingo-Santos,Victoria Galán Sánchez-Seco,Andrés Labiano-Fontcuberta, Ana Gómez-López,Paula Salgado-Cámara,Lucienne Costa-Frossard, Enrique Monreal,Susana Sainz de la Maza,Jordi A Matías-Guiu,Jorge Matías-Guiu,Alfonso Delgado-Álvarez,Paloma Montero-Escribano,María Luisa Martínez-Ginés,Yolanda Higueras,Lucía Ayuso-Peralta,Norberto Malpica,Helena Melero

Multiple sclerosis (Houndmills, Basingstoke, England)（2023）

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摘要

RIS patients had abnormal brain connectivity in major resting-state neural networks and worse performance in neurocognitive tests. This entity should be considered not an "incidental finding" but an exclusively non-motor (neurocognitive) variant of multiple sclerosis.

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关键词

Radiologically isolated syndrome, multiple sclerosis, functional connectivity, resting-state neural networks

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