Yin Yang 1 promotes the neuroendocrine differentiation of prostate cancer cells via the non-canonical WNT pathway (FYN/STAT3).

Rui-Ji Liu,Zhi-Peng Xu,Xiang Huang,Bin Xu,Ming Chen

Clinical and translational medicine（2023）

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摘要

We identified YY1 as a novel dysregulated transcription factor that plays an important role in NEPC progression in this study. We believe that an in-depth investigation of the mechanism underlying YY1-mediated disease may lead to improved NEPC therapies.

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关键词

prostate cancer cells,yang,prostate cancer,neuroendocrine differentiation,pathway

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